China Wholesale Rosuvastatin Calcium 10 Mg Tab Manufacturers - Pitavastatin Calcium – CPF
China Wholesale Rosuvastatin Calcium 10 Mg Tab Manufacturers - Pitavastatin Calcium – CPF Detail:
| 匹伐他汀钙 | Pitavastatin | 147526-32-7 | In-House |
| PI-5 | 3800-06-4 | In-House | |
| PI-6 | 145516-11-4 | In-House | |
| PI-7 | 121660-11-5 | In-House |
Description
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Anti-cancer activity.
Background
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
Storage
4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Chemical structure

Related Biological Data

Proposal 18 Quality Consistency Evaluation projects which have approved 4, and 6 projects are under approving.

Advanced international quality management system has laid solid foundation for sales.

Quality supervision runs through the whole life cycle of the product to ensure the quality and therapeutic effect.

Professional Regulatory Affairs team supports the quality demands during the application and registration.
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To be the stage of realizing dreams of our employees! To build a happier, more united and more professional team! To reach a mutual benefit of our customers, suppliers, the society and ourselves for China Wholesale Rosuvastatin Calcium 10 Mg Tab Manufacturers - Pitavastatin Calcium – CPF , The product will supply to all over the world, such as: Netherlands, UK, St. Petersburg, We have more than 200 staff including experienced managers, creative designers, sophisticated engineers and skilled workers. Through hard work of all employees for the past 20 years own company grew stronger and stronger. We always apply the "client first" principle. We also always fulfill all contracts to the point and therefore enjoy excellent reputation and trust among our customers. You are very welcome to personally visit our company.We hope to start a business partnership on the basis of mutual benefit and successful development . For more information please do no hesitate to contact us..
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